My favorite show was always Prairie Home Companion, which they could never get on podcast anyway. But I stopped listening to it after Garrison Keillor left anyway.
And though a bit niche, if you enjoy world-class mandolin playing, you'll do far worse than Chris Thile. Man, mandolin or not, if you just enjoy good musicianship, give it a listen.
The name of the show has changed to Live From Here for anyone interested.