What big problems would you like to see solved?
By big problems, I mean those addressing problems that are both important and urgent. Interpret that as you like.
By solved, I mean, for the most part, solved by people like those who participate in forums like HN. Which in turn probably also implies a solution that is web-based, or at least tech-based. Again, interpret as you like. I'm not looking to narrow the scope of this question too much.