I likewise question the efficacy of efforts like eradicating malaria. I can't help but feel all that money would be better spent on technology (not startups, but like fusion and other energy research, nanotech, space industry etc), even if for-profit. Like, no mater how many Africans you can save from malaria, they will keep dying or living shitty lives because of poverty, famine, wars... Only technology can actually change the world (and politics, but we can't really seem to be able to do much about that...).