There are different types of feeling good, and the purely chemical good isn't particularly rewarding. There are the moments in life where you are happy because you are living the life you want to live, and those are way better than just feeling good from drugs. Sometimes life goals and drugs come together, and that gets really interesting. It's reasonably common for people to do MDMA and have a glimpse of their life without anxiety and trauma, or LSD and looking at their own existence objectively.
For me, the best moments in my life are around building connections with people.