On a technical note, the Art Institute of Chicago images are being served using an API called IIIF, which allows you to scale, extract regions of interest, etc. [1]. There are about 1-2B images worldwide being served from museums and libraries using the API [2] and viewers that can work with the content from multiple institutions at the same time, for instance to compare two van Gogh self-portraits from different museums: http://projectmirador.org/demo/
[1] https://iiif.io/api/image/2.1/#image-request-uri-syntax [2] https://iiif.io/community/#participating-institutions