The slippery glass back and round sides kills me. (Ducttapped the back panel/sides as a decent fix, black tape nobody ever asks, probly just think I'm poor eh)
Not happy with the weight on my pinky either. (Two hands required.) Size similar issue, can't type with one hand like I could with the nexus 5. There is a screen shrink feature but it's awkward and the weight is the real issue.
Software being non stock is annoying but you get used to it quick enough.
Other than those issues it's pretty decent.
Enjoying the 4k video, wide angle photos and software stabilizer a lot.
The dual Sim or sim+ micro SD feature comes in handy for travel/video shooting.
I probably wouldn't recommend unless you have money to burn or really need the video.
Something cheaper probably has relatively same specs/features.