There's about 10 shark attacks per year in the U.S. Now that you know that, will you stay out of the ocean forever? Or will you maybe take the risk and go for a dip if you go on a beach vacation?
edit Plus, of those 40 cases the vast majority are from swimming in lakes. So there's only a handful of cases where the infection was due to neti-pot usage. I could only find 3 confirmed cases. That's extremely rare.
No but I might avoid areas known to host sharks.
Crossing the street once is more dangerous.
https://healthywa.wa.gov.au/Articles/A_E/Amoebic-meningitis https://www.cdc.gov/parasites/naegleria/pathogen.html https://www.abc.net.au/news/2018-03-20/professor-encouraging...
There is a similar problem where cleaning contact lenses with untreated water leaks to Acanthamoeba infection, leading to possible blindness of loss of an eye.
We all weigh risk against convenience. This is very low risk.