I’d be hard-pressed to think of a time it made a lick of difference to me, having lived in the U. S. my entire life. “Don’t carry a handgun to Chicago”, okay, file that one away. “If you’re black”, and I’m not, “don’t stop for gas in Martinsville, IN”. Though that one might not still be true, I’d still stay away from Elwood, my Afro-American friend.
Other than that, with the caveat of being a white male, I can’t say I’ve ever had need to pay attention.