Could you elaborate on the kind of discrimination you're thinking of? I'm sure people who can't see have a harder time getting jobs (and for sure have to work harder to overcome things like websites with screen-reader-hostile content), but I'm not sure if you're referring to subconscious discrimination or explicit discrimination.
The subconscious stuff is harder to deal with because it might not even hit a surface level. On the other hand, the open hostility that the LGBTQ+ people faced was easier to 'diagnose' or recognize, and thus begin dealing with.