Yeah, you'd still definitely want to look at the toolpaths. As far as recalculating everything, it could still calculate most of it ahead of time.

What I'm thinking of is something like a CAM workspace in FreeCAD. That is, something like would let you take your model, generate and inspect a toolpath (or flip through possible toolpaths), and produce a part. The CAM software would get feedback from the controller, so it could follow what was going on.

It might also be possible to make adjustments, or pause the run, based on sensors. For instance, if you could detect chatter, you could slow down the feed rate; if you could detect a broken tool, you could pause the run and ping the operator.