I don't have any sensors to get a real idea of the difference in CO2 it makes, but it allows us to run the furnace less at night (heat from the lights), and makes a noticeable difference in humidity ( very dry air here ).
Also, we get about 1-2 family meals / week of food at full capacity ( total 4x8 grow space and 800 watts of light running only at night ).
Not economical and takes a lot of maintenance, but it's a fun hobby from which we all feel the benefits.