I can't imagine anything that is practical, fits in its lane, and can also fly efficiently. Not saying that it can't be done, but I have a hard time envisioning what it might look like.
I currently own a Jeep. My dad once owned a Pinto.
Who in their right mind would think "You know, this is the perfect car to strap some wings to!" for either of these vehicles?
That's just giving the middle finger to the god's of flight begging for a quick death.
Again, in the the flying Pinto's case - that's what happened.