Since these tools are not in general obfuscated to hide their activities from the users and don't perform extra work to conceal things like how many recipients there are for each message or session, there are lots of possible avenues for noticing anomalies.
We aren't arguing that there is no way to create communications tools that prevent users from detecting if their communications are being intercepted. Instead, we're arguing that those tools wouldn't be simple, straightforward variants on existing end-to-end encrypted messaging systems.