The sinus headaches are a physical reaction though. It's from constriction of the sinuses. When you take these it relaxes and the snot in your nose drains. I had sinus headaches for 23 years (not realizing they were sinus headaches), took all sorts of headache pills, they were ineffective. These are effective for me, I do not think it is placebo.

Psychology actually says this is because you're telling your brain that this simple pain should be handled by the meds you're taking so your brain considers that to be an error.

Manufacturers should start selling bottles of pills that contain a percentage of identical placebo pills at a discount - Perhaps you switch to Tylenol 50%, then Tylenol 25%, then end up at Tylenol Homeopathy version?