Even without the recent coke plant fire, Pittsburgh had a record worst year (since they've cleaned up in the past few decades at least) for days of high airborne particulates, warnings for those with asthma, etc.
The gas wells in the south west of the state used to pool their run off/waste water (which contains at least benzene IIRC) and wait for it to evaporate off. Those pools occasionally leaked though, and the pictures of dead fish in nearby ponds/streams looked bad. So now they mist the water and spray it into the air to be dispersed over a larger area. Last time I was home I saw my neighbor mowing his yard with a white surgical mask on.
Tap water has turned cloudy at best and isn't trusted by anyone, so everybody buys bottled water, which just increases pollution again.
Last I read though, Bayer was getting out of Pittsburgh, and BNYM was doing a bunch of layoffs. As much as they should, I can't imagine the local govts bringing down the hammer anytime soon. In leiu of tax breaks, Appalachia has a long history of selling the environment and locals health in exchange for business.