There are some diseases that involve a malfunction in phenylalanine processing, like phenylketonuria[1] and hyperphenylalaninemia[2]. It would not surprise me a bit if people with subclinical forms of hyperphenylalaninemia self-medicate with diet soda to feel better, particularly energy drinks that come with other things that aid in dopamine synthesis. Disfunction in dopamine synthesis often affects other things like NO synthesis, affecting blood pressure and inflammation.
[0] https://en.wikipedia.org/wiki/Aspartame?wprov=sfla1
[1] https://en.wikipedia.org/wiki/Phenylketonuria?wprov=sfla1
[2] https://en.wikipedia.org/wiki/Hyperphenylalaninemia?wprov=sf...
Edit: changed serotonin to epinephrine, as phenylalanine is not a precursor to serotonin.