I would love to Alpine all the things, it's just so fast to work with, BUT musl makes things hard, especially if you're over in Pythonland - packages with C dependencies, if built, are only built for glibc, so when installing them on Alpine, one has to have a compiler, development headers etc. Makes things too slow and error prone.

Otherwise it's a great distro and I use it for non-Pythonic stuff or for Python with no dependencies.