95% of the times when they respond with "I don't have a Github|StackOverflow profile" they prove to be juniors or time wasters applying for a high salary. That's fine if I'm looking for a junior but they often apply for senior positions.
I trust the data on these two as I consider it to be really difficult to get by as a programmer without decent activity on at least one platform. HAving code out there, IMHO, adds better than any CV. It's just data but it helps me get a clearer view.