1. Honey bees in North America are a non-native invasive species.
2. Virtually all honey bees in the United States are livestock.
3. Colony collapse disorder is an economic issue for commercial beekeepers, and apparently not much of a problem.
4. The true threat to honey bees in the United States isn't environment, but rather the introduction of the Varroa destructor mite in 1987 (which eradicated feral honey bees).
A "honey bee sanctuary" in the continental US is a weird idea.