This is already an issue in that the author of the post refuses to call a Trans-woman a Trans-woman... but instead prefers to call them a man. So the Twitter post is already implicitly transphobic.
Note: Transgender people are natural. The village of Salinas in Dominican Republic more or less proves that a genetic basis for transgender exists. https://www.washingtonpost.com/news/morning-mix/wp/2015/09/2...
The scientific understanding of gender, transgender, and sex has greatly improved in just the last 30 years. Unfortunately, the old concepts of male and female are now outdated in the face of modern science.
https://www.mayoclinic.org/diseases-conditions/ambiguous-gen...
These are the bodies that the creator have given us. Yes, I'm religious, and I do believe that we must accept the bodies and the facts-of-the-bodies that we were created with. By studying sexuality and gender, new medical understandings have come about. There is more than just Male (XY) and Female (XX), there's a spectrum in between due to medical mysteries (from chromosome mutations, like Klinefelter syndrome XXY chromosomes... to the "guevedoce" (Translation: Penis at 12) born-females who turn into males at the age of 12ish.
There's just a lot of weird medical stuff and mysteries that happen in this world.
Its hard to argue with how God created us. It seems like the best plan moving forward is to accept these ambiguous gendered people and study them... and accept them for how they are.