A person with a disability shouldn't be denied any given job because an application is inaccessible even though the job function itself ought to be accessible (e.g., for a blind person, isn't inherently visual). It follows that every line of business application that can be accessible must be accessible. This is why I call this out whenever I learn about an inaccessible UI toolkit. I'm afraid that an inaccessible app will lead to someone being unable to get a job they want, or losing the one they have.