I tried coke, heroin and meth once each. Coke was a huge let down, and I've had no interest in trying that again. Meth, on the other hand -was eye-opening. I knew from my experience that if I did it again, I would end up overdosing on it very quickly -so I never did.
I'm far from a health nut or religious freak. I drank like a fish for decades, did pot, did LSD. Booze was hard enough (pot and LSD both reached a point where they were no longer fun, so I no longer did them) to quit, I'm glad that was the only thing that stuck.
So yeah ...I'm glad -and lucky, that I had the experiences with the hard stuff that I had. When meth got common it held zero temptation for me, ditto for coke and heroin.
It helps that I have always been poor as dirt and knew that I wouldn't be able to have regular access to any of that, either.