For reference you need to use Cloudfront to back S3 static sites (kinda sucky) to get SSL - We do that on prod but we also use netlify for dev (we could for both, but AWS existed before in out estate, accounting etc)
I don't mind AWS, but Netlify was just painless.
In similar fashion I use now.sh, I could upload a thing to s3 and fiddle with permissions and settings, or I could `now` :)
There is no restriction on S3 bucket regions.