I don't have a huge problem with this, mainly because it's my understanding that there are like 700 toxins in traditional smoking and that nicotine itself is actually not considered very unhealthy.
Also, the liquid refills can contain an acutely toxic concentration of nicotine. Enough to kill a small child with as little as half a teaspoon ingested or absorbed through the skin. [2]
1. https://www.ncbi.nlm.nih.gov/pubmed/?term=25794473
2. https://www.aappublications.org/content/early/2014/12/12/aap...
(Anyway, I'd like to see a similar survey about traditional cigarettes.)