The main killer of course being that they dropped support for exFAT, so there's zero way to use Dropbox on a drive shared between OS. That sounds a bit niche, but it basically means Dropbox can't be used on external storage.
Don't get me wrong, exFAT is dated. However, the supported file systems vary between OS, so you can't even use Tuxera (or FUSE) NTFS on Mac.
There's a lot of complaints about this on the Dropbox forums; so they know, they just don't care. So that's a black mark both technically and for customer support.