I had severe depression and I was a victim of such experiments. I lost two years of my life to these drugs and failed suicide two times at the end. What helped me get out of this mess was CBT therapy to change the way I think about things and how to deal with emotions, how to defuse going into the loops of sadness. I didn't need any drugs but doctors insisted it will make me feel better.
Yes, I was feeling better initially - actually sometimes I could feel the effects to similar to those of cannabis. But after few months I was getting hallucinations, weird thoughts and sudden urges to kill myself. The doctors response was to change the dose or try different one. I think this should be illegal.