> However, I live in the real world, with real patients. I live in a world where I can tell a patient that a mole is completely benign and it still makes them anxious and they want me to cut it out.

What I am saying is that things need to change, not that this is a trivially fixable problem. Exactly how you would change things is not obvious to me, but I would say that not doing tests because of the information hazard issue is a symptom that something is wrong.

Perhaps the more general version of this problem is "don't set up systems that give billions of people nonconstructive negative feedback". It's applicable beyond medicine, I would point at unrealistic celebrity beauty ideals as another manifestation.