Comment by thorwasdfasdf | Hacker News Reader

Comment by thorwasdfasdf | Hacker News Reader

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There have been a number of experiments where they gave patients more magnesium, and in response most patients reduce their depression by a statistically significant amount. The inverse was found when they gave them calcium (more calcium increases depression). It's all about the ratio of calcium to magnesium. We're a society that consistently gets way too much calcium and way too little magnesium. That's because our food source isn't diverse. Dairy is considered a food group here in the US, and almost everything in it comes from Milk, is primarily made up of milk. Milk is very unbalanced in terms of Calcium to magnesium, something like 10 to 1 ratio.

Also, there was another study where they found that treatments for depression actually increased serum magnesium levels in the brain.

EDIT: Here is the study: https://www.ncbi.nlm.nih.gov/books/NBK507265/# "A dietary supplement of 500mg calcium immediately and severely worsened MD, which was extinguishable within one hour by orally treating with 400mg gel capsules of Mg as magnesium glycinate "

I stated up front that somatopsychic effects are quite real. I don't doubt that a magnesium deficiency is a culprit in depression for many people.

But are you arguing that, yea, verily, this article's foundational assumption is true and correct: Magnesium deficiency is the sole or prime cause of all (or virtually all) modern depression?

If so, I think you need to back that up with a whole lot more than a paragraph or two about things you've read, like a long list of citations that not only show the role magnesium plays, but also another long list of citations that affirmatively excludes myriad other potential causes of Major Depression that are generally understood to be contributing factors.

I don't think the article is saying it's the sole cause but they're saying it's a factor.

And of course, not everyone who gets too little mag/too much calcium will react in the same way.

From the article:

inadequate dietary Mg is prevalent in America and is the most likely cause.

It contains zero qualifiers suggesting it is one of many factors, a major factor among many, etc. It uses the word "the" and the singular form of "cause."

You skipped right over "most likely" and only focused on "the ... cause". To me it sounds like they are saying statistically Mg deficiency is the most widespread underlying factor. Their language is strong, but it does not come off that absolutist and the "most likely" suggests other causes.

I'm a freelance writer by trade. I sometimes write health articles. I could not say what this article says about cause.

At best, I could say something like "Given the proven widespread lack of adequate dietary magnesium and the known side effects of magnesium insufficiency, it seems plausible to suggest that at least some portion of the increase in depression is due to widespread magnesium deficiency."

That may seem like quibbling to you, but scientists get paid to quibble about the details and to be as precise as humanly possible. They should be meeting at least as high a standard as my generally low paid freelance writing.

> There have been a number of experiments where they gave patients more magnesium, and in response most patients reduce their depression by a statistically significant amount

Can you link to those studies please?

> more calcium increases depression

now that really is curious. Again, do you have a link? TIA

please check edit.

Which specific studies were those?

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