I don’t know that web pages would have have access to user chrome settings but I still have to ask, do any of those changes make browser fingerprinting easier?
This is a great question the honest answer is I don't know. That said, I would be incredibly surprised if web pages had access to the settings in that file.
Likely anything that changes the size of the viewport helps with fingerprinting, including tab location/size and even showing/hiding the bookmark bar. It's not just browser settings either; if you're using DisplayFusion's snap points like I do to have a border around maximised windows, fingerprinting is probably very easy.