Human's average lifespans have been a lot shorter throughout history.
According to Our World In Data [1] a 20-year-old would expect to live to 60 in 1850 (before penicillin), versus to 80 now.
[1] https://ourworldindata.org/life-expectancy#it-is-not-only-ab...
This means first grandchildren in early 40s (rather than late 50s), and first great grandchildren by mid 60s (rather than mid 80s)