I'm reading a lot about WebAssembly (which, I know, it's not a programming language per se), and more recently Dark (https://darklang.com).
My open question is whether in the coming 2-3 years there will be a significant paradigm shift in programming languages, or not.
My bet is that a combination of new, purpose-specific languages, together with "real" AI, will have a chance to have a big impact.