I think the interruption thing is interesting - at jobs where I was solo, I probably minded it significantly more. With constant pairing, different interruptions can be handled in different ways. Two-second questions can be answered by the non-driver while the driver continues to focus. Five minute answers should probably stop both members, but having two brains allows you to bounce back into context through re-merging your mental model of where you left off.
Thinking about this though, I realized that in pairing you have internal interruptions as well - if one person needs to use the bathroom or take a phone call, the other can choose to keep working and maintain context. When the breaker returns they can reload their mental models much more easily. Or you can both take breaks and you've already got a built-in ping-pong opponent ready to play :)