http://faculty.washington.edu/dcatling/Catling2009_SciAm.pdf
Helium is produced from natural gas wells but with the prices for the gas where they have been for so long no one bothers to capture it - it's not worth it, it's just vented to the atmosphere and escapes.
So "running out of helium" basically means "running out of cheap helium and the price will go up until it establishes a balance with the cost of producing it from the ground instead of a government storage tank".
For as long as we get natural gas out of the ground, we will have helium.
Namely, the known quantity of a resource that can be extracted in an economical viable manner using current technologies.
So there are a number of variables that can affect the size of a reserve that have nothing to do with how much of the resource is known to exist.
I often wonder what it will be like for the next intelligent species/civilization that develops on earth. With all the easily accessible resources already mined will get get stuck in the steampunk age? Sure there might still some left where we could find it with advanced equipment, but not if you're just starting out.
Do planets essentially get one shot at advanced civilization?
Not sure if this is practical. In contrast to ore which is basically rock and more-or-less pure iron (or other desired metal), automobiles are a wild mix of different alloys which would have to be extensively processed (if this is possible in the first place). With plastics, the situation is similar if not worse, given that not all plastics melt, and burned fuel is burned and cannot be recovered at all.
The only thing where our civilizational waste can be used is if someone invents a Star Trek replicator clone.