I've been staring at a desktop screen 6h+ daily for 8y+ and started feeling serious rsi symptoms on my right wrist at the old age of 19.
I tried bandages and wraps in the beginning, but once I started lifting all pains literally disappeared.
Heavy deadlifts (and maybe a press), done with correct form, is something that I'm quite sure will resolve the issue for the majority of people -- when your wrist starts being able to manage 200lbs+ loads then mouse-related issues feel like a joke.
I'd be interested in hearing stories where deadlifts didn't help. Would there be any?