Of course the future is uncertain. I don't know that if my going to work tomorrow is not going to rip a hole in the space time continuum, but I'll risk it anyway. I know that's being facetious, but the point remains. There are clear and obvious dangers with current practices. They are not sustainable. One can never say for certainty that any change may not have unintended consequences, but in this case, they are being actively identified and mitigated so a repeat of issues associated with synthetic and organic pesticide is less likely.

For me (and this is only my opinion), a highly targeted dsRNA, which is completely organic (it's not synthesised), has no synthetic modifications, is present in massive quantities in nature, is consumed every day by every person on earth if they're had fruit or vegetables, does not persist in the environment, is likely much safer than any existing pesticide, synthetic or organic.

As for selective pressure, current broad spectrum pesticides, synthetic or organic, would cause greater ecological disruption I would think. Again, my point is that this is an attempt to remove that pressure, not add to it.

Saying it's all too hard to predict, so let's do nothing, just doesn't seem sensible to me. The risks of not acting seem clear and obvious. Have a look at the talks in the OECD link I provided, and you'll see there's a pretty precautionary approach being taken. It's not a case of 'let's have a go and see if it works. What could go wrong?'