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> Plastic as such is quite a inert material.

Certain plastics are used for implants - there must be a good reason for it? Bioreactivity, rejection, degradation? Those and other reasons might be a concern to be thought about in regards to inhaled plastic fibers.

Not to mention if there were issues with the fibrous nature itself (like "fibrous minerals" cause certain diseases)...

Nearly everything you put in body like silicone, plastic, titanium have known negative effects.

Even food they say!

Some plastics are endocrine disruptors.

Isn't that more about the solvents that are used when manufacturing them? I would expect them to be gone by the time they turn to such small particles

Depends on the plastic. There was the whole thing with BPAs not that long ago.