Is R/O better? Depends on your definition of better, but R/O is obviously very clean and safe to drink, although I have heard some people say they don't like the taste or "how" it feels. R/O removes a lot of the minerals so it does taste different for sure. Some people can't stand their water to be hard and some don't like soft water, so I think that is preference for many people.
My 2 cents, is you should evaluate your specific water and area to be safe (it is fairly inexpensive). For example, where I live in Florida we are on well water which comes from the aquifer which basically the vast majority of Florida's drinking water comes from. The quality of the water varies through the year, and changes quite a bit based on rainfall etc. We use a storage tank to off-gas the water and then a series of filters and a softener to improve the water quality (I installed UV this year too). I also send our water out yearly to get it tested by a certified lab (was recommended to me to do that), and we always send 2 samples, one from inside the house and one direct from the well. This helps us determine the true water quality and whether we have a system issue etc. I just had this done like 2-3 weeks ago for this year, and direct from the well was perfectly healthy to drink and well within all EPA guidelines, and our filtering did improve the water some but left the minerals mostly unchanged which is by design in my setup.
R/O will clean your water very well, I looked at installing a whole house system in the past, but it also removes a lot of the minerals that are good for us too. So since our water is clean we chose to not get an R/O. On my boat, I have a water maker which essentially is an R/O type system and I can tell the difference between it and my house, but honestly I have no preference myself. R/O systems do require more maintenance and cost more to operate, but I cannot say anything bad about them if you are worried about water quality. The only bad thing is they are not cheap to acquire or maintain for a whole house system.
edit to add this: BTW -- if you are on city/county water and not well, the city/county is required to maintain quality reports and usually they test daily multiple times a day. I dated a girl one time who works for a city doing that type of work. You can request the reports from them as they are public record. Then you can also have your house water tested for usually <$100 at a certified lab and know for sure where you stand.