Not really. Google ultramarathoning, Humans are incredibly well designed to run long distances at a sustained pace, it's like the one other thing we rock at better than other animals other than intelligence.
A sprinter is wasted after 100m. A marathon runner is wasted after 26.2 miles. Then there are the ultra marathoners. I believe the analogy holds.
Humans evolved to be really good at long distance running and given proper training, time and discipline you can run an absurd distance compared to most mammals.