Manifest V3 and killing web.request API were the reasons that finally convinced me to go back to Firefox. Almost a month later, I didn’t find a single thing that would make me go back to Chrome.
My main complaint about fresh Firefox installations is that it takes a lot of time to fine tune everything. Every single time I have spend hours changing settings in about:config, from disabling telemetry, Pocket, changing networking/DNS settings, pipelining etc. Vanilla installation is just not well optimized.