USPTO is now first to file, not first to invent. Prior art becomes less and less useful over time.
Prior art is still relevant WRT patent prosecution. The AIA made several changes to patent law, perhaps most notably making the effective filing date the determining factor for purposes of applying prior art, instead of the invention date. This means interferences no longer occur. There are also now different post-grant procedures for challenging patent validity.
Source: am a patent agent Disclaimer: this is not legal advice