Comparing new WiFi model to new 3G model, out of airplane mode, the 3G drains about 2x to 3x faster than WiFi model.
> A single charge lasts up to six (6) weeks, based on a half hour of reading per day with wireless off and the light setting at 13. [0]
We were still pretty pissed at the blatant false advertising (a hardcore book reader reads for only a half hour a day!?!), but moving forward, she keeps the device in airplane mode 95% of the time, only turning it off to download whatever new book she just bought. It increased to at least 2-3 weeks after that, instead of a single week.
[0] https://www.amazon.com/Kindle-Paperwhite-Waterproof-Storage-...
You can keep the display of the kindle on for hours at a time with minimal drain
Of course, modern e-readers have a backlight. Though you can never fully turn it off, at least on my first-gen Paperwhite, which is unfortunate.