Programming and general computing, it's still possible to write and run any code in your PC, but big companies will be trying to control it.

For example the DRM shenanigans in the GPU, or, when you can't write code for your smartphone unless you have permission from its parent company, and even with permission, you still can't write "any" arbitrary code - only some parts of the system are available to you. I'm aware of the exploits and jailbreaks, but those will not be always available.