Yeah, we ran a minor upgrade to our cluster earlier this week and it knocked out the entire cluster for over two hours, and we were getting AWS specific errors regarding hostname headers that we've never gotten before. I managed to get a developer advocate on twitter to lend us a hand, but if I had actually waited on support things would likely still be down.
Unfortunately that seems more like a trend with AWS- there are a lot of new services that feel like they're 80% ready for production, but which are being sold as complete solutoins.