With a traditional publisher you usually get a royalty of about 10-15% versus 4-6 times that with print on demand. Announce publication on YC and let bloggers promote with amazon affiliate links. Everyone wins but Barnes and Noble.
When you print on demand, your printing costs are twice as high per copy, but since there's no middleman, you make more as an author. Of course, it's impossible to distribute, so it doesn't really matter. It's only a good option if you really only intend to sell a few copies to friends and family.
It's just like the equity equation. Also, being published once makes it easier in the future should you desire to go that route, while self publishing does not.
The way I see it, a writer self-publishing is like a hacker building his own servers and running them from his basement.