StackExchange reaches 16 million users, 131% growth
blog.stackoverflow.com
blog.stackoverflow.com
Initially with SE you had to pay to setup your own SE site. As mentioned in the post, they found that the sites were doing poorly without the critical mass of people to answer questions. Creating Area 51 helped them objectively measure topic interest, and allowed users to determine whether the site had legs or not, and thusly validate whether the site was worth creating. Had they not done this, I don't think we'd be reading about such success today.
[1]: http://blog.stackoverflow.com/2010/05/migration-of-se-1-0-si...
The key is to create a community of people with common interest, where there is enough interest (Area 51) and have them connected. Getting answers is a side effect. They have nailed this part and you have to give it to them.
For what it is worth, questions that doesn't belong in a site are automatically, and generally quickly moved.
This says that last August they had around 86K users, so by now they should have around 100K. The huge visitor to user ratio is a sign of their success, I think. (I'm assuming SO represents most of their traffic)
Edit: Wikipedia page says: "As of September 2010, Stack Overflow has about 243,000 registered users"