Second known interstellar visitor after Oumuamua
science.sciencemag.org
science.sciencemag.org
Although that's still complicated space ballet.
We can even imagine technologies that survive a 50 km/s impact. Like self-replicating nanobots based on tardigrades, stashed in the interior of an asteroid - plenty of people already think life has been spread in asteroid-planet collisions. But we definitely don't have those now.
Now imagine a spaceship that travels 100 light years. It's going to pass through roughly 10^15 1km "voxels" on its journey, which means the chances of it hitting one of those 1km rocks is ~(10^15/10^29) or 1 in 100 trillion. Space is biiiig.
The real danger, though, is the smaller stuff. It's hard to know the distribution of interstellar dust size, but there are a LOT more small things than big things, and it only takes a grain of sand at relativistic speeds to cause a really bad day. If sand-sized rocks turn out to be 100 trillion times more common than these big ones, well, that's going to be a problem...
Of course these calculations also tend not to consider staging, just like the "reaching the moon is impossible" calculations prior to Apollo.
All hail our new overlords