I think if one has a statistics class that's aimed at giving people better statistics literacy it would be a remarkably good fit for a gamified interactive curriculum using an in class currency to make bets/predictions!
You could earn currency the same way you do in games, completing mundane tasks you really don't want to do, like having every homework problem you successfully complete give you a few gold. This incentivizes studying and the effort adds some real emotional value to the currency you wager later.
You could have a whole final fantasy style rpg underlayer where currency is used to buy armor/weapons to make you stronger and help you fight bigger monsters for more currency and advancing in the "game" with the ultimate goal of amassing enough currency through your activities to "buy" your A in the class or whatever.
Then you could have the meat of the class be in lecture scenarios where everyone is presented with a situation that's implicitly meant to test your knowledge of a common gotcha in statistical literacy like base rate neglect in a live statistical simulation. You get to watch as your characters are subjected to "rolls" of the dice that determine their fate based on if you chose A or B. Do you believe the wizard with the diagnosing spell with a x rate of false positive/negative who says you have disease such and such with a y incidence rate?
It's just the basic base rate neglect fallacy scenario, but putting people in a situation where they're incentivized to care about it and rewarded for getting it right.
And by doing these simulations live in class it makes for a lot of spectacle and fun with everyone getting to gamble on these scenarios and then get to see the results play out in real time with all the suspense that gambling normally entails.
You could even have group scenarios where the entire class has to pick option a or b as a whole with everyone's money collectively on the line, and have a heated discussion period where different parties are trying to explain why the class should choose a or b. Imagine being the sole voice of reason trying to valiantly explain to your class how base rate neglect works with everything on the line!
This just seems like such a natural fit to me, and I'm really excited thinking about it.