A 10Gbit connection at HE is going to cost you roughly $2,000/month, or about $65/day.

That will serve your 49MB video roughly 2 million times a day.

Let’s go with 50% average utilization, and say that means we need to monetize roughly 0.0065 cents per view to cover the bandwidth cost.

I think YouTube charges something like 10 cents per ad view, but won’t charge if the user clicks Skip in that 5 second window. I’m not sure what percent of views result in a billable ad, but anecdotally I’ve heard it’s surprisingly high.

I would assume storage is a much bigger cost factor, to say nothing of paying the engineers to develop and support the infrastructure.

I don't think that's quite right. 1TB/mo of CloudFront bandwidth is $90/mo (per [1]). Also, that's the on-demand price. The price with volume discounts is much lower.

[1]: https://calculator.s3.amazonaws.com/index.html#s=CloudFront&...