ARM binaries available? Great. You're all set. (hopefully its for the right generation of ARM though, I can't get SteamLink software to run on my pinebook because it does raspberry pi hardware version checks that obviously fail).
Not available? You're gonna run into one of two scenarios:
Closed source app? Sorry. Just never going to get it (unless you want to run it through qemu at a huge performance hit and YMMV).
Open source app? Compile it yourself! Which takes noticeably longer than x86 for me. Maybe in server this works out. For desktop, compiling st myself was actually the path of least resistance to getting a terminal I liked. I wouldn't have wanted to compile firefox on ARM though without some serious server horsepower. When I used to build docker images they would sometimes take hours, for things that were less than a minute on x86.