Not this one. The answer is yes, we will run out of helium, it is one of the few truly non-renewable resources. You can use chemical processes to make methane or petroleum-equivalents, and coal can be replaced with charcoal, but once all the helium atoms have drifted off into space, they're gone forever.
It just won't happen soon.
FYI, our sun is also going to go out.
Just so you can plan ahead.
We’ll be able to fuse our own before that happens. Or go fetch it from elsewhere.